Cerebellar atrophy in neuromyelitis optica spectrum disease (NMOSD) patients

Resumo

Neuromyelitis Optica Spectrum Disease (NMOSD) is an autoimmune neurodegenerative process which affects the optic nerve and spinal cord in inflammatory outbreaks, leading to its symptons. Newly, recent studies have showed that other structures in central nervous system (CNS), like the brain cortex, thalamus and medulla oblongata are affected too. The increased use of different techniques of magnetic resonance imaging (MRI) analysis, such the voxel-based morphometry (VBM), has improved our knowledge about the real CNS damage in NMOSD patients.