Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS
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Palavras-chave

Metabolomic profile
Factorial planning
Biological fluids.

Como Citar

FILLIETTAZ, Flavia Presta; CANTU, Ana Valeria Colnaghi Simionato; DUARTE, Gustavo H. B.; EBERLIN, Marcos N.; POPPI, Ronei J. Exploring methodologies to obtain the metabolomic profile of biological fluids by LC/MS-MS. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 26, 2019. DOI: 10.20396/revpibic262018454. Disponível em: https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/454. Acesso em: 18 mar. 2026.

Resumo

The investigation of methodologies to obtain the metabolomic profile of blood serum from healthy individuals by LCMS/MS was performed by factorial planning and the number of molecular features as the system answer. Sample preparation, chromatographic and ionization source conditions were optimized, defining the best conditions to obtain the metabolomic profile of biofluids to be applied in future identification of potential tumor biomarkers.

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Copyright (c) 2019 Flavia Presta Filliettaz, Ana Valeria Colnaghi Simionato Cantu