No. 26 (2018), Resumos
No. 26 (2018)

Conjugated Zn(II) complex as metallo-?-lactamase model

Resumos
Published 2019-02-15
Raphael Honorato Ribeiro
Universidade Estadual de Campinas
Camilla Abbehausen
Universidade Estadual de Campinas
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Keywords

Metallo-β-lacatamase
Biomimetics
Conjugated complexes.

How to Cite

RIBEIRO, Raphael Honorato; ABBEHAUSEN, Camilla. Conjugated Zn(II) complex as metallo-?-lactamase model. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 26, 2019. DOI: 10.20396/revpibic2620181185. Disponível em: https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/1185. Acesso em: 22 apr. 2026.
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Abstract

This work reports the synthesis, characterization and the interaction with a ?-lactam compound of a Zn(II) complex containing imidazole and pyridil groups bearing a free carboxylate for peptide conjugation. The complex was able to interact with the carboxilate next to the ?-lactam group of amoxicillin and the conjugation with peptide (glutathione as a model) was successful.

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Copyright (c) 2019 Raphael Honorato Ribeiro, Camilla Abbehausen