Synthesis and Characterisation of Poliurethanic Hydrogel Based on Poly(2-ethyl-2-oxazoline) (PEtOx) and Polycaprolactone (PCL)

Abstract

Polyurethanes are versatile materials, whose properties can be tailored by their composition. In this work, segmented polyurethanes based on poly(2-ethyl-2-oxazoline) and polycaprolactone, hydrophilic and hydrophobic segments, respectively, and biocompatible segments, were synthesized and characterized with respect to composition, thermal properties and swelling in water as a function of temperature and cell viability. The combination of these macrodiols resulted in amphiphilic, thermoresponsive and biocompatible polyurethanes.