n. 27 (2019), Resumos
n. 27 (2019)

Evaluation of the antifungal activity and antibiofilm of the essential oil of Ocimum canum (Alfavaca) in Candida spp

Resumos
Publicado 2019-11-30
Aline Marques
Universidade Estadual de Campinas
Jose Hofling
Universidade Estadual de Campinas
https://orcid.org/0000-0002-6054-0688
Natália Carrasco
Universidade Estadual de Campinas
Sarah Pimenta
sarahreispimenta@gmail.com
Giovana Boni
Universidade Estadual de Campinas
Simone de Feiria
Universidade Estadual de Campinas
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Palavras-chave

Candida spp
Ocimum spp
Medicinal plants

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MARQUES, Aline; HOFLING, Jose; CARRASCO, Natália; PIMENTA, Sarah; BONI, Giovana; FEIRIA, Simone de. Evaluation of the antifungal activity and antibiofilm of the essential oil of Ocimum canum (Alfavaca) in Candida spp. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 27, p. 1–1, 2019. DOI: 10.20396/revpibic2720193044. Disponível em: https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/3044. Acesso em: 26 out. 2025.
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Resumo

Essential oils from plants of the genus Ocimum have demonstrated potential for anti-Candida action, as described in the literature. The objective of the present project was to evaluate the antifungal activity against Candida spp. and the antibiofilm effect of C. albicans of O. canum essential oil. The essential oil showed antifungal activity between 0.0062 to 1 mg / mL and effect on metabolic activity of the biofilm by up to 50% at concentrations of 16-1 mg / mL. The essential oil demonstrates antifungal activity against Candida spp. and decreases the metabolic activity of C. albicans when in biofilm in formation and mature.

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