No. 27 (2019), Resumos
No. 27 (2019)

Biological effect of Ocimum gratissimum (Alfavacão) essential oil in Candida spp

Resumos
Published 2019-11-30
Natália Carrasco
Universidade Estadual de Campinas
Jose Hofling
Universidade Estadual de Campinas
https://orcid.org/0000-0002-6054-0688
Sarah Pimenta
Universidade Estadual de Campinas
Aline Marques
Universidade Estadual de Campinas
Simone de Feiria
Universidade Estadual de Campinas
Giovana Boni
Universidade Estadual de Campinas
PDF (Portuguese)

Keywords

Ocimum gratissimum
Candida spp
Biofilm

How to Cite

CARRASCO, Natália; HOFLING, Jose; PIMENTA, Sarah; MARQUES, Aline; FEIRIA, Simone de; BONI, Giovana. Biological effect of Ocimum gratissimum (Alfavacão) essential oil in Candida spp. Revista dos Trabalhos de Iniciação Científica da UNICAMP, Campinas, SP, n. 27, p. 1–1, 2019. DOI: 10.20396/revpibic2720193066. Disponível em: https://econtents.sbu.unicamp.br/eventos/index.php/pibic/article/view/3066. Acesso em: 26 oct. 2025.
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Abstract

The use of medicinal plants is a millenarian practice and plays an important role in the development of commercial drugs. Therefore, the present project aimed to determine the antimicrobial activity of Ocimum gratissimum essential oil through the broth microdilution test and evaluate the effect of the essential oil on biofilm formation by Candida albicans. The results showed antifungal activity between 0.25 and 1 mg/mL and decrease of the metabolic activity of C. albicans biofilm between 8-0,5 mg/mL. The essential oil demonstrates antifungal activity against Candida spp. and decreases the metabolic activity of C. albicans when in biofilm formation.

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